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pentobarbital decreases amounts of toremifene by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. CYP3A4 inducers improve price of toremifene metabolism, reducing the constant-state concentration in serum.

pentobarbital will lower the level or effect of theophylline by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.

fentanyl transdermal and pentobarbital both enhance sedation. Stay away from or Use Alternate Drug. Limit use to sufferers for whom different treatment alternatives are insufficient

pentobarbital decreases effects of hemin by pharmacodynamic antagonism. Use Caution/Keep track of. Drugs that raise delta-aminolevulinic acid synthetase may perhaps decrease hemin outcome.

pentobarbital will decrease the level or impact of montelukast by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Not known.

pentobarbital will minimize the extent or effect of pitolisant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Intently. Pitolisant exposure is lowered by 50% if coadministered with powerful CYP3A4 inducers.

pentobarbital will lessen the level or outcome of diazepam buccal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of. Robust or average CYP3A4 inducers may well enhance charge of diazepam elimination; consequently, efficacy of diazepam could possibly be decreased.

pentobarbital will decrease the level or effect of aprepitant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.

pentobarbital will lessen the extent or result of lorlatinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism.

pentobarbital will decrease the level or influence of erlotinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.

pentobarbital will lower the level or influence of pioglitazone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unknown.

pentobarbital will lower the extent or impact of netupitant/palonosetron by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Netupitant is mainly metabolized by CYP3A4; prevent use in patients who're chronically working with a strong CYP3A4 inducer

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pentobarbital will lessen the level or outcome of nimodipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Not known.